BDBM150812 US8981106, 2 (SX-576)::USRE47267, Compound 2

SMILES OB(O)c1ccc(OC(F)(F)F)cc1CSc1ccc(cn1)C(=O)Nc1ccc(F)cc1

InChI Key InChIKey=AEDMWJARWOMJKQ-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150812   

TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Syntrix Biosystems

Curated by ChEMBL
LigandPNGBDBM150812(US8981106, 2 (SX-576) | USRE47267, Compound 2)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at CXCR1 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Syntrix Biosystems

Curated by ChEMBL
LigandPNGBDBM150812(US8981106, 2 (SX-576) | USRE47267, Compound 2)
Affinity DataIC50:  31nMAssay Description:Inhibition of CXCR1 (unknown origin) transfected with RBL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed